the Pythagorean Order of Death
dedicated to restoring Atlantean Democracy
"composite-ccr12.pdf" =
Competing Memes Propagation on Networks:
A Case Study of Composite Networks
ABSTRACT
If a false rumor propagates via Twitter, while the truth prop-
agates between friends in Facebook, which one will prevail?
This question captures the essence of the problem we ad-
dress here. We study the intertwined propagation of two
competing “memes” (or viruses, rumors, products etc.) in
a composite network. A key novelty is the use of a com-
posite network, which in its simplest model is deﬁned as a
single set of nodes with two distinct types of edges inter-
connecting them. Each meme spreads across the composite
network in accordance to an SIS-like propagation model (a
ﬂu-like infection-recovery). To study the epidemic behav-
ior of our system, we formulate it as a non-linear dynamic
system (NLDS). We develop a metric for each meme that
is based on the eigenvalue of an appropriately constructed
matrix and argue that this metric plays a key role in de-
termining the “winning” meme. First, we prove that our
metric determines the tipping point at which both memes
become extinct eventually. Second, we conjecture that the
meme with the strongest metric will most likely prevail over
the other, and we show evidence of that via simulations in
both real and synthetic composite networks. Our work is
among the ﬁrst to study the interplay between two compet-
ing memes in composite networks.
"jbc.M114.561761.full.pdf" =
Targeting CB2 -GPR55 Receptor Heteromers
Modulates Cancer Cell Signaling
ABSTRACT
The G protein-coupled receptors CB2
(CB2R) and GPR55 are overexpressed in cancer
cells and human tumors. As a modulation of
GPR55 activity by cannabinoids has been
suggested, we analyzed whether this receptor
participates in cannabinoid effects on cancer
cells. Here, we show that CB2R and GPR55
form heteromers in cancer cells, that these
structures possess unique signaling properties,
and that modulation of these heteromers can
modify the antitumoral activity of cannabinoids
in vivo. These findings unveil the existence of
previously unknown signaling platforms that
help explain the complex behavior of
cannabinoids and may constitute new targets
for therapeutic intervention in oncology.
Tags:
9711200 =
The Large N Limit of Superconformal ﬁeld theories and supergravity
Abstract
We show that the large N limit of certain conformal ﬁeld theories in various dimen-
sions include in their Hilbert space asector describing supergravity on the product of
Anti-deSitter spacetimes, spheres and other compact manifolds. This is shown by taking
some branes in the full M/string theory and then taking a low energy limit where the ﬁeld
theory on the brane decouples from the bulk. We observe that, in this limit, we can still
trust the near horizon geometry for large N. The enhanced super symmetries of the near
horizon geometry correspond to the extra supersymmetry generators present in the super-
conformal group (as opposed to just the super-Poincare group). The't Hooft limit of 3+1
N=4 super-Yang-Mills at the conformal point is shown to contain strings: they are IIB
strings. We conjecture that compactiﬁcations of M/stringtheory on various Anti-deSitter
spacetimes is dual to various conformal ﬁeld theories. This leads to a new proposal for a
deﬁnition of M-theory which could be extended to include ﬁve non-compact dimensions.
14104089v1 =
Entanglement entropy in Galilean conformal ﬁeld theories and ﬂat holography
We present the analytical calculation of entanglement entropy for a class of two dimensional
ﬁeld theories governed by the symmetries of the Galilean conformal algebra, thus providing a rare
example of such an exact computation. These ﬁeld theories are the putative holographic duals to
theories of gravity in three-dimensional asymptotically ﬂat spacetimes. We provide a check of our
ﬁeld theory answers by an analysis of geodesics. We also exploit the Chern–Simons formulation of
three-dimensional gravity and adapt recent proposals of calculating entanglement entropy by Wilson
lines in this context to ﬁnd an independent conﬁrmation of our results from holography.
A deterministic model for forecasting long-term solar activity
Eleni Petrakou∗
Center for Axion and Precision Physics Research, Institute for Basic Science (IBS),
Daejeon 34141, Republic of Korea
February 2, 2017
Abstract
The successive long-term increase and decrease in Sun’s activity associated with solar cycles has not been connected to a definite underlying mechanism so far, hence predictions about its amplitude usually depend on extrapolation from the sunspot number of previous cycles or observations of the geomagnetic field, becoming available only very close to or after a cycle’s start and often departing from the actual events. Here we present a phenomenological model for quantitative description of the cycles’ characteristics in terms of the number of M-class flares.
The main element of the model is the relative ecliptic longitude of the planets Jupiter and Saturn. Using as input the temporal distribution of M-class flares during cycle 21, we obtain distributions for cycles 22-24 in notable agreement with the observed ones. Elements of shorter-term description can be elaborated further, however we are able to provide predictions for the evolution of solar activity for the rest of cycle 24 and for cycle 25. This deterministic description could contribute to elucidating the underlying physical mechanism and forecasting space weather.
Temporal association of certain neuropsychiatric Disorders Following Vaccination of children and adolescents:
a Pilot case–control study
Background: Although the association of the measles, mumps, and rubella vaccine with autism spectrum disorder has been convincingly disproven, the onset of certain brain-related autoimmune and inflammatory disorders has been found to be temporally associated with the antecedent administration of various vaccines. This study examines whether antecedent vaccinations are associated with increased incidence of obsessive– compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children.
Bounding the speed of gravity with gravitational wave observations
The time delay between gravitational wave signals arriving at widely separated detectors can be used to place upper and lower bounds on the speed of gravitational wave propagation. Using a Bayesian approach that combines the first three gravitational wave detections reported by the LIGO collaboration we constrain the gravitational waves propagation speed c_gw to the 90% credible interval 0.55 c < c_gw < 1.42 c, where c is the speed of light in vacuum. These bounds will improve as more detections are made and as more detectors join the worldwide network. Of order twenty detections by the two LIGO detectors will constrain the speed of gravity to within 20% of the speed of light, while just five detections by the LIGO-Virgo-Kagra network will constrain the speed of gravity to within 1% of the speed of light.
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