the Pythagorean Order of Death

dedicated to restoring Atlantean Democracy

"composite-ccr12.pdf" =

Competing Memes Propagation on Networks: 

A Case Study of Composite Networks 

ABSTRACT 

If a false rumor propagates via Twitter, while the truth prop- 

agates between friends in Facebook, which one will prevail? 

This question captures the essence of the problem we ad- 

dress here. We study the intertwined propagation of two 

competing “memes” (or viruses, rumors, products etc.) in 

a composite network. A key novelty is the use of a com- 

posite network, which in its simplest model is defined as a 

single set of nodes with two distinct types of edges inter- 

connecting them. Each meme spreads across the composite 

network in accordance to an SIS-like propagation model (a 

flu-like infection-recovery). To study the epidemic behav- 

ior of our system, we formulate it as a non-linear dynamic 

system (NLDS). We develop a metric for each meme that 

is based on the eigenvalue of an appropriately constructed 

matrix and argue that this metric plays a key role in de- 

termining the “winning” meme. First, we prove that our 

metric determines the tipping point at which both memes 

become extinct eventually. Second, we conjecture that the 

meme with the strongest metric will most likely prevail over 

the other, and we show evidence of that via simulations in 

both real and synthetic composite networks. Our work is 

among the first to study the interplay between two compet- 

ing memes in composite networks.

"jbc.M114.561761.full.pdf" =

Targeting CB2 -GPR55 Receptor Heteromers

Modulates Cancer Cell Signaling 

ABSTRACT 

The G protein-coupled receptors CB2 

(CB2R) and GPR55 are overexpressed in cancer 

cells and human tumors. As a modulation of 

GPR55 activity by cannabinoids has been 

suggested, we analyzed whether this receptor 

participates in cannabinoid effects on cancer 

cells. Here, we show that CB2R and GPR55 

form heteromers in cancer cells, that these 

structures possess unique signaling properties, 

and that modulation of these heteromers can 

modify the antitumoral activity of cannabinoids 

in vivo. These findings unveil the existence of 

previously unknown signaling platforms that 

help explain the complex behavior of 

cannabinoids and may constitute new targets 

for therapeutic intervention in oncology.

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9711200 =

The Large N Limit of Superconformal field theories and supergravity

Abstract 

We show that the large limit of certain conformal field theories in various dimen- 

sions include in their Hilbert space asector describing supergravity on the product of 

Anti-deSitter spacetimes, spheres and other compact manifolds. This is shown by taking 

some branes in the full M/string theory and then taking a low energy limit where the field 

theory on the brane decouples from the bulk. We observe that, in this limit, we can still 

trust the near horizon geometry for large N. The enhanced super symmetries of the near 

horizon geometry correspond to the extra supersymmetry generators present in the super- 

conformal group (as opposed to just the super-Poincare group). The't Hooft limit of 3+1 

N=4 super-Yang-Mills at the conformal point is shown to contain strings: they are IIB 

strings. We conjecture that compactifications of M/stringtheory on various Anti-deSitter 

spacetimes is dual to various conformal field theories. This leads to a new proposal for a 

definition of M-theory which could be extended to include five non-compact dimensions.

14104089v1 =

Entanglement entropy in Galilean conformal field theories and flat holography

We present the analytical calculation of entanglement entropy for a class of two dimensional 

field theories governed by the symmetries of the Galilean conformal algebra, thus providing a rare 

example of such an exact computation. These field theories are the putative holographic duals to  

theories of gravity in three-dimensional asymptotically flat spacetimes. We provide a check of our 

field theory answers by an analysis of geodesics. We also exploit the Chern–Simons formulation of 

three-dimensional gravity and adapt recent proposals of calculating entanglement entropy by Wilson 

lines in this context to find an independent confirmation of our results from holography.

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A deterministic model for forecasting long-term solar activity

Eleni Petrakou
Center for Axion and Precision Physics Research, Institute for Basic Science (IBS),

Daejeon 34141, Republic of Korea

February 2, 2017

Abstract

The successive long-term increase and decrease in Sun’s activity associated with solar cycles has not been connected to a definite underlying mechanism so far, hence predictions about its amplitude usually depend on extrapolation from the sunspot number of previous cycles or observations of the geomagnetic field, becoming available only very close to or after a cycle’s start and often departing from the actual events. Here we present a phenomenological model for quantitative description of the cycles’ characteristics in terms of the number of M-class flares.

The main element of the model is the relative ecliptic longitude of the planets Jupiter and Saturn. Using as input the temporal distribution of M-class flares during cycle 21, we obtain distributions for cycles 22-24 in notable agreement with the observed ones. Elements of shorter-term description can be elaborated further, however we are able to provide predictions for the evolution of solar activity for the rest of cycle 24 and for cycle 25. This deterministic description could contribute to elucidating the underlying physical mechanism and forecasting space weather. 

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Temporal association of certain neuropsychiatric Disorders Following Vaccination of children and adolescents:

a Pilot case–control study

Background: Although the association of the measles, mumps, and rubella vaccine with autism spectrum disorder has been convincingly disproven, the onset of certain brain-related autoimmune and inflammatory disorders has been found to be temporally associated with the antecedent administration of various vaccines. This study examines whether antecedent vaccinations are associated with increased incidence of obsessive– compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children. 

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